

Pragmatic leader experienced in using real-world evidence to improve health
Nancy A. Dreyer, MPH, PhD, FISPE
Seasoned Business Leader/ Serial Entrepreneur/ Expert in Real-World Evidence
Nancy Dreyer is Adjunct Professor of Epidemiology at the University of North Carolina at Chapel Hill and a Trustee of Brandeis University. Recently retired from full-time employment as the Chief Scientific Officer for IQVIA Real World Solutions, she is well-known for her thought leadership and a popular public speaker. She has helped advance the use of real-world evidence for clinical decision support and regulatory purposes, influencing the content of guidelines by regulators in the US, Europe, and China, each of which cite one or more of her publications. Her experience includes biopharmaceutical, occupational and environmental research.
​
Her substantial executive and field experience have helped hone her pragmatic views.
Profile overview
Areas of expertise
Education & Fellowships
Recent External highlights
35+ years of experience in epidemiology and business including​
-
IQVIA SVP and Chief Scientific Officer
-
Quintiles/Outcome Sciences Inc, SVP, Chief of Scientific Affairs
-
i3 Research/Ingenix, UnitedHealth Group, SVP
-
Epidemiology Resources, Inc. and the New England Epidemiology Institute, CEO & Chair of the Board
-
Developing reliable real-world evidence (RWE), including person-generated health data
-
Regulatory use of RWE for market authorization and label expansion
-
Assessing the relevance and reliability of RWE for decision support
-
Health data linkage
-
BA, Brandeis University
-
Master of Public Health, Epidemiology, University of North Carolina
-
PhD, Epidemiology, University of North Carolina
-
Fellow, International Society of Pharmacoepidemiology & the Drug Information Association
-
Chief Scientific Advisor, Picnic Health
-
Adjunct Professor of Epidemiology, Gillings School of Public Health, University of North Carolina, Chapel Hill, NC
-
Drug Information Association Scientific & Policy Advisory Council and former Director
-
Duke-Margolis Center for Health Policy Research Planning Board
-
Brandeis University, Trustee
Selected Recent Publications
-
Largent JA, Xie X...and Dreyer NA. Cognitive and other neuropsychiatric symptoms in COVID-19: Analysis of person-generated longitudinal health data from a community-based registry, BMJ Open 2023 ;13:e069118. doi:10.1136/ bmjopen-2022-069118
-
Dreyer NA. Strengthening evidence-based medicine with real-world evidence. Invited Commentary. Lancet Healthy Longevity 2022 Oct;3(10):e641-e642. doi: 10.1016/S2666-7568(22)00214-8. Epub 2022 Sep 20. PMID: 36150401.
-
Dreyer NA, Reynolds MW, Albert L, Brinkley E, Kwon T, Mack C, Toovey S. How frequent are acute reactions to COVID-19 vaccination and who is at risk? Vaccine 2022; 40 (12): 1904-1912.
-
Sridhara R, Marchenko O, Jiang Q, Barkdsale E. Chen J, Dreyer N et al. Evaluation of treatment effects in underrepresented populations in cancer trials: Discussion with international regulators. Statistics in Biopharmaceutical Research 2022:1-7
-
Reynolds MW, Xie Y, Knuth KB, Mack CD, Brinkley E, Toovey S, Dreyer NA. COVID-19 vaccination breakthrough infections in a real-world setting: Using community reporters to evaluate vaccine effectiveness. Infection and Drug Resistance 2022:15 5167–5182.
-
Helantera I, Snuyder J, Asberg A. Cruzado JM ...and Dreyer A. Demonstrating Benefit-Risk Profiles of Novel Therapeutic Strategies in Kidney Transplantation: Opportunities and Challenges of Real-World Evidence. Transplant International 2022; 3:35:10239/ti.2022.10329. eCollection 2022